Introductory Chapter: Myelodysplastic Syndromes
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منابع مشابه
Range Determination of Antigen Expression in Myeloid, Erythroid and Lymphoid Cell Lineages among Patients with Myelodysplastic Syndrome
Background: Myelodysplastic syndrome is a mixed clonal disorder of bone marrow progenitor cells. Understanding the pattern of the different lineage-specific, immature, and mature markers in myelodysplastic syndrome will help in setting-up the frame of reference to diagnose. Patients and Methods: We compared 60 bone marrow samples from 30 newly-diagnosed patients with myelodysplastic syndrome ...
متن کاملInfections in myelodysplastic syndromes.
Myelodysplastic syndromes are associated with a risk of severe infections. While neutropenia is likely to be the main predisposing factor, several other immune defects have been reported, including impaired neutrophil function, B-, T- and NK-cell defects and the possible consequences of iron overload due to red blood cell transfusions. The advanced age of most patients, their frequent comorbidi...
متن کاملThe Role of Mathematics on Human Structure
This book explores the mathematical view of selected body systems and organs and as claimed by its author, “it has an objective to facilitate modern treatment with mathematical precision.”The author, Dr. Adhikari has PhD in mathematics and is the Head of the Institution and Department of Mathematics, Ghusuri Uchcha Madhyamic Vidyalaya, West Bengal, India. The motivation of the author in writing...
متن کاملIDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.
BACKGROUND Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia. Heterozygous missense mutations in IDH1 at position R132 and in IDH2 at positions R140 and R172 have recently been reported in acute myeloid leukemia. However, little is known about the incidence and prognostic impact of IDH1 and ID...
متن کاملActivation of cytotoxic T-cell receptor gd T lymphocytes in response to specific stimulation in myelodysplastic syndromes
Results Vγ9Vδ2 T cells, the major circulating γδ T-cell subset, were reduced in myelodysplastic syndromes, but mainly in myelodysplastic syndromes’ patients with associated autoimmune diseases, suggesting that this anomaly was largely due to the autoimmune component. On the other hand, bromohalohydrin pyrophosphate-induced expansion of the Vγ9Vδ2 T-cell population in all 15 control samples, but...
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تاریخ انتشار 2017